What Is The Most Effective Joint Supplement?

Many people, especially as they get older, will experience ongoing discomfort in their knees, hands, elbows, shoulders, and other joints throughout their bodies.

What Is The Most Effective Joint Supplement?

This condition is almost always brought on by osteoarthritis, which is the most common form of arthritis. In the United States, roughly one-quarter of the population has been found to suffer from this particular form of arthritis.

Pain medicines like Tylenol or nonsteroidal anti-inflammatory drugs like ibuprofen (brand name: Advil) are typically the first line of defense when it comes to treating joint pain.

Additionally, there are dozens of supplements on the market that promise to relieve joint pain, but with so many options out there, it can be hard to find the most effective ones. 

To help you out, we’ve made this list of the top 6 best supplements to take to help with joint pain. Most of these can be picked up at your local drug store/pharmacy, though you could always buy them online if you’re struggling to find what you want. 

Keep reading to find the best joint pain supplement for you!


One of the most well-liked dietary supplements for the treatment of pain, particularly the discomfort in the joints that comes with osteoarthritis, is turmeric.

The chemical component curcumin, which is found in turmeric, is responsible for the pain-relieving benefits of the spice, as curcumin can reduce inflammation in the body.

The typical recommended daily dosage of turmeric is between two and four times 500 milligrams. An analysis of studies indicated that turmeric improves symptoms of joint pain and may be comparable to ibuprofen.


Glucosamine is a natural molecule that can be found in cartilage. Cartilage is a substance that stops bones from rubbing against each other, which can be painful and lead to inflammation. This supplement may also help avoid the degradation of cartilage that might occur with arthritis.

Supplements typically contain either glucosamine hydrochloride or glucosamine sulfate, both of which are forms of the amino sugar glucosamine.

According to research, medicines containing glucosamine hydrochloride do not significantly alleviate the joint discomfort brought on by osteoarthritis.

But a different study says that glucosamine sulfate is effective in relieving these symptoms; so, it may be preferable to glucosamine hydrochloride as a treatment choice.

When used for an extended time, glucosamine sulfate has the potential to help slow down the course of osteoarthritis. When used for up to three years, studies suggest that it slows down the process of narrowing of the joint space, which is a hallmark of the condition getting worse. 

In most cases, a single dose of 1,500 milligrams of glucosamine sulfate is administered once daily (mg). If you find that this causes abdominal distress, try breaking it up into three doses of 500 milligrams each.


SAMe S-adenosyl-L-methionine, also known as SAMe, is a dietary supplement that’s frequently used to alleviate the symptoms of osteoarthritis and depression. 

Methionine is an amino acid, and your liver is the organ that naturally generates SAMe from it. It contributes to the creation of cartilage as well as its repair, which is just one of its many uses.

What Is The Most Effective Joint Supplement?

When taken in supplement form, SAMe has been shown to alleviate some of the joint discomforts that are associated with osteoarthritis. There is a possibility that it will be just as efficient as the anti-inflammatory medicine celecoxib (Celebrex). 

SAMe is often administered in doses ranging from 200 to 400 milligrams (mg) three times daily. Remember that it may take some time before you see benefits from your efforts.

Avocado-Soybean Unsaponifiables

Unsaponifiables derived from avocado and soybean oils are referred to as ASUs, and they are a form of extract that may help prevent the breakdown of cartilage. It also has the potential to aid in the repair of cartilage.

Patients with osteoarthritis who take ASUs experience a greater reduction in their pain symptoms compared to those who take a placebo.

A daily dose of 300 milligrams (mg) of ASU is considered to be standard.

Fish Oil

Docosahexaenoic acid and eicosapentaenoic acid are both types of omega-3 fatty acids found in fish oil, and both of these acids have been shown to have anti-inflammatory benefits.

Those who suffer from rheumatoid arthritis and use fish oil supplements may experience a reduction in symptoms such as joint discomfort. However, it does not appear to alleviate the symptoms of osteoarthritis.

Doses of fish oil typically range from 300 mg to 1,000 mg daily.


In the same way as glucosamine contributes to the formation of cartilage, chondroitin does the same thing. It also may aid in the prevention of cartilage degeneration caused by osteoarthritis.

Chondroitin can lessen osteoarthritic patients’ joint discomfort and stiffness. People who take chondroitin for knee pain saw a reduction of at least 20 percent in their symptoms around half the time, according to one study. 

Chondroitin sulfate, when taken over a long time, may also help to halt the course of osteoarthritis. When used for up to two years, studies demonstrate that it reduces the rate at which the joint space becomes congested.

Chondroitin and glucosamine are frequently seen together in joint supplements. However, it is not yet known whether taking a combination supplement is any more beneficial than taking just one of the supplements separately.

Chondroitin is normally used in a dose ranging from 400 to 800 milligrams (mg) two or three times a day.


When there are so many options to choose from, it can be difficult to choose a dietary supplement that effectively treats joint pain.

Multiple components can be found in the majority of these goods. It’s important to keep in mind that a better product does not necessarily result from a lengthy list of ingredients. 

Remember, the Food and Drug Administration of the United States does not have jurisdiction over these items; so, it is important to carefully study product labels to be sure you know what you’re ingesting. 

Talk to your primary care physician or pharmacist about the other drugs you are currently taking before making a decision on which dietary supplement to take.

This will allow them to check for any possible drug interactions. Certain drugs, such as blood thinners, have the potential to interact negatively with certain joint health supplements.

Lindsey Morgan
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